Acute myeloid leukemia AML is cancer that starts inside bone marrow. This is the soft tissue in the center of bones that helps form all blood cells. The cancer grows from cells that would normally turn into white blood cells. Note multiple Auer rods which are found only in acute myeloid leukemias, either myeloblastic or monoblastic. These rods consist of clumps of azurophilic granule material.
Symptoms of Leukemia
Acute myelogenous leukemia - Symptoms and causes - Mayo Clinic
You may also hear it referred to as M3 AML. While it is similar in many ways to the other subtypes, APL is distinctive and has a very specific treatment regime. Treatment outcomes for APL are very good, and it is considered the most curable type of leukemia. The genetic abnormality or mutation most often seen in the DNA of the leukemia cells is a translocation between chromosomes 15 and Promyelocytes are cells that fall in line in the development of these type of white blood cells, with the "babies" being myeloblasts or blasts, and the adults being the myelocytes known as neutrophils, eosinophils, basophils, and monocytes. Promyelocytic leukemia cells can be compared to human teenagers.
Acute myeloid leukemia - adult
Leukaemia is cancer of the white blood cells. Acute leukaemia means it progresses rapidly and aggressively, and usually requires immediate treatment. Acute leukaemia is classified according to the type of white blood cells affected. The two main types of white blood cells are:. The following types of leukaemia are covered separately:.
The symptoms of leukemia may be very subtle at first and include fatigue, unexplained fever, abnormal bruising, headaches, excessive bleeding such as frequent nosebleeds , unintentional weight loss, and frequent infections, to name a few. These, however, can be due to a wide range of causes. If related to leukemia, symptoms may hint at the type of the disease that is present, but many symptoms overlap and are not this specific. Leukemia cannot be diagnosed based on symptoms alone, but an awareness of them can suggest when further evaluation is needed.